Article

Single nucleus multiomic atlas of human dorsal root ganglia reveals the contribution of non-neuronal cell types to pain

2025-09-22

Abstract excerpt

Sensory neurons residing in dorsal root ganglia (DRG) transmit sensory information such as pain, itch, touch, pressure and bodily position to the central nervous system. The activity of sensory neurons is regulated by non-neuronal cell types in the DRG, including satellite glial cells (SGCs) and fibroblasts. Dysregulated gene expression in DRG cells contributes to sensory nervous system disorders such as chronic p...

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Literature Corpus work: edfaff6e-a4ba-5fd9-b2a0-c453d3f73255
DOI: 10.1101/2025.09.21.677655

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