Article

Spatial, transcriptomic and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

2022-04-05

Abstract excerpt

<h4>Summary</h4> Key mechanisms underlying chronic pain occur within the neural circuitry of the dorsal horn. Recent genome-wide association studies (GWAS) have identified genetic variants associated with the predisposition to chronic pain. However, most of these variants lie in regulatory non-coding regions that have so far not been linked to spinal cord function. Here, we take a multi-species approach to determ...

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Literature Corpus work: 4dc2d4f0-cbef-5a81-b411-a287a39b3504
DOI: 10.1101/2022.04.01.486135

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