Article

Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs

2017-04-24

Abstract excerpt

Cytosine-5 RNA methylation plays an important role in several biologically and pathologically relevant processes. However, owing to methodological limitations, the transcriptome-wide distribution of this mark has remained largely unknown. We previously established RNA bisulfite sequencing as a method for the analysis of RNA cytosine-5 methylation patterns at single-base resolution. More recently, next-generation s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7ee80aff-bedf-5cfd-9767-9bc1c4cf8ac3
DOI: 10.1101/130419

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAsDOI 10.1101/130419Read

The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs.Semantic proximity Read

GeneDMRs: an R package for Gene-based Differentially Methylated Regions analysisSemantic proximity Read

Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeRSemantic proximity Read

Novel enzyme-based reduced representation method for DNA methylation profiling with low inputsSemantic proximity Read

Comparative analysis of the Illumina Mouse Methylation BeadChip and Reduced Representation Bisulphite Sequencing for routine DNA methylation analysis of murine samplesSemantic proximity Read

Single-cell genome-wide bisulfite sequencing uncovers extensive heterogeneity in the mouse liver methylome.Semantic proximity Read

m5C-Atlas: a comprehensive database for decoding and annotating the 5-methylcytosine (m5C) epitranscriptome.Semantic proximity Read

Detection and analysis of RNA methylationSemantic proximity Read

New guidelines for DNA methylome studies regarding 5-hydroxymethylcytosine for understanding transcriptional regulationSemantic proximity Read

Contribution of Intragenic DNA Methylation in Mouse Gametic DNA Methylomes to Establish Oocyte-Specific Heritable MarksSemantic proximity Read

Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6Semantic proximity Read

Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome.Semantic proximity Read