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Maintaining structural and functional homeostasis of the <i>Drosophila</i> respiratory epithelia requires stress-modulated JAK/STAT activity

2020-06-19

Abstract excerpt

<h4>Summary</h4> Signaling mediated by the Janus kinase (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway is critical for maintaining cellular and functional homeostasis in the lung. Thus, chronically activated JAK/STAT signaling is causally associated with lung diseases such as lung cancer, asthma, and chronic obstructive pulmonary disease. To elucidate the molecular processes that transform...

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Literature Corpus work
7edb198c-c9d9-58b7-99f1-218cfa4fc60b
DOI
10.1101/2020.06.19.160929
Open publication

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Maintaining structural and functional homeostasis of the <i>Drosophila</i> respiratory epithelia requires stress-modulated JAK/STAT activityDOI 10.1101/2020.06.19.160929
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