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Article

Jumu is required for the activation of JAK/STAT in Drosophila lymph gland development and epidermal wounds.

Biochemical and biophysical research communications - 5 Feb 2022

Hao Yangguang, Pan Jichuan, Chen Qing, Gu Heze, Ji Guanglin, Yue Guanhua, Yang Shuting

Abstract excerpt

The regulatory mechanism of hematopoiesis and innate immunity in Drosophila is highly similar to that in mammals, and Drosophila has become a suitable model to understand vertebrate hematopoiesis and the immune response. JAK-STAT signaling pathway components are widely conserved during evolution, and contribute to hematopoiesis and multiple tissue damage and immune responses. Here, we demonstrate that Stat92E is...

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Identifiers

PMID: 34999256
DOI: 10.1016/j.bbrc.2021.12.115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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