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Article

A Goldilocks principle of JAK/STAT signaling governs airway epithelial homeostasis and stress adaptation in <i>Drosophila</i>

2025-05-21

Abstract excerpt

<h4>Summary</h4> Airway epithelia must maintain barrier integrity while continuously adapting to changing environmental conditions. This requires key signaling pathways in airway epithelia to operate within a tightly controlled functional range. Here, we show that airway epithelial homeostasis in Drosophila depends on balanced JAK/STAT signaling. Basal pathway activity is constitutively present in differentiated...

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Literature Corpus work
155a0e5b-c31e-5538-acc5-95e95a919e40
DOI
10.1101/2025.05.20.655050
Open publication

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A Goldilocks principle of JAK/STAT signaling governs airway epithelial homeostasis and stress adaptation in <i>Drosophila</i>DOI 10.1101/2025.05.20.655050
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