Article

Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems

2023-10-10

Abstract excerpt

Gene manipulation strategies using germline knockout, conditional knockout, and more recently CRISPR/Cas9 are crucial tools for advancing our understanding of the nervous system. However, traditional gene knockout approaches can be costly and time consuming, may lack cell-type specificity, and can induce germline recombination. Viral gene editing presents and an exciting alternative to more rapidly study genes of...

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Literature Corpus work: 7ebb2478-934a-5b29-ae1f-dd75b9cfbaa0
DOI: 10.1101/2023.10.10.561249

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