Article

An improved CRISPR/dCas9 interference tool for neuronal gene suppression

2020-05-27

Abstract excerpt

The expression of genetic material governs brain development, differentiation, and function, and targeted manipulation of gene expression is required to understand contributions of gene function to health and disease states. Although recent improvements in CRISPR/dCas9 interference (CRISPRi) technology have enabled targeted transcriptional repression at selected genomic sites, integrating these techniques for use...

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Literature Corpus work: dfd79db2-aa8c-559d-a4bd-fa4bb80f73fe
DOI: 10.1101/2020.05.26.116822

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