Article

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates, and humans

2018-10-04

Abstract excerpt

<h4>Summary</h4> Targeting genes to specific neuronal or glial cell types is valuable both for understanding and for repairing brain circuits. Adeno-associated viral vectors (AAVs) are frequently used for gene delivery, but targeting expression to specific cell types is a challenge. We created a library of 230 AAVs, each with a different synthetic promoter designed using four independent strategies. We show that...

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Identifiers and source

Literature Corpus work: e5afb323-f7e2-56e9-be63-52b6629aa9b2
DOI: 10.1101/434720

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