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Improved transformation efficiency of group A <i>Streptococcus</i> by inactivation of a type I restriction modification system

2021-02-23

Abstract excerpt

Streptococcus pyogenes or group A Streptococcus (GAS) is a leading cause of bacterial pharyngitis, skin and soft tissue infections, life-threatening invasive infections, and the post-infectious autoimmune syndromes of acute rheumatic fever and post-streptococcal glomerulonephritis. Genetic manipulation of this important pathogen is complicated by resistance of the organism to genetic transformation. Very low tran...

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Identifiers and source

Literature Corpus work
7e9d2beb-ca5a-5523-817a-e78118faae28
DOI
10.1101/2021.02.23.432441
Open publication

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Improved transformation efficiency of group A <i>Streptococcus</i> by inactivation of a type I restriction modification systemDOI 10.1101/2021.02.23.432441
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