Article

Methylome-dependent transformation of <i>emm</i> 1 group A streptococci

2023-04-10

Abstract excerpt

Genetic intractability presents a fundamental barrier to the manipulation of bacteria, hindering advancements in microbiological research. Group A Streptococcus (GAS), a lethal human pathogen currently associated with an unprecedented surge of infections world-wide, exhibits poor genetic tractability attributed to the activity of a conserved type 1 restriction modification system (RMS). RMS detect and cleave spec...

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Literature Corpus work: 9dbe34ef-9d7d-560c-a342-adeb9a8dbd94
DOI: 10.1101/2023.04.10.536284

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