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Sortase A promotes virulence in experimental Staphylococcus lugdunensis endocarditis

14 Aug 2013

Abstract excerpt

Staphylococcus lugdunensis is a commensal of humans and an opportunistic pathogen. It can cause an aggressive form of infective endocarditis in healthy humans akin to Staphylococcus aureus. Here we compared the virulence of the genome-sequenced S. lugdunensis strain N920143 to S. aureus in an experimental rat endocarditis model. N920143 caused a milder course of disease with lower levels of bacteraemia and...

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PMID: 23943787
DOI: 10.1099/mic.0.070292-0

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