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Article

Improved transformation efficiency of group A Streptococcus by inactivation of a type I restriction modification system.

PloS one - 1 Jan 2021

Finn Meredith B, Ramsey Kathryn M, Tolliver Hunter J, Dove Simon L, Wessels Michael R

Abstract excerpt

Streptococcus pyogenes or group A Streptococcus (GAS) is a leading cause of bacterial pharyngitis, skin and soft tissue infections, life-threatening invasive infections, and the post-infectious autoimmune syndromes of acute rheumatic fever and post-streptococcal glomerulonephritis. Genetic manipulation of this important pathogen is complicated by resistance of the organism to genetic transformation. Very low...

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Share to DNA Restriction-Modification Enzymes
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33914767
DOI: 10.1371/journal.pone.0248201
PMCID: PMC8084154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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