Article

Genome-wide prediction and integrative functional characterization of Alzheimer’s disease-associated genes

2021-02-10

Abstract excerpt

The mechanism of Alzheimer’s disease (AD) remains elusive, partly due to the incomplete identification of risk genes. We developed an approach to predict AD-associated genes by learning the functional pattern of curated AD-associated genes from brain gene networks. We created a pipeline to evaluate disease-gene association by interrogating heterogeneous biological networks at different molecular levels. Our analys...

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Literature Corpus work: 571cd64e-940f-51b9-abd3-78b86f8dabc1
DOI: 10.1101/2021.02.09.430536

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