Article
Integrated Bioinformatics and Ensemble Learning Reveal Diagnostic Modeling and Drug Discovery in Alzheimer’s Disease
2025-11-26
Abstract excerpt
<title>Abstract</title> <p> <bold>Background:</bold> Alzheimer’s disease (AD) is driven by complex molecular and immune dysregulation, yet reliable diagnostic biomarkers and druggable targets remain limited. This study aimed to identify key AD-associated regulatory genes, characterize their immune and spatial expression features, and prioritize small-molecule compounds with therapeutic potential. <bold>Methods...
Topics
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- Alzheimer's disease research and treatments
- ATP Synthase and ATPases Research
- Bioinformatics and Genomic Networks
- Cholinesterase and Neurodegenerative Diseases
- Dementia and Cognitive Impairment Research
- GDF15 and Related Biomarkers
- Mitochondrial Function and Pathology
- Neuroinflammation and Neurodegeneration Mechanisms
Identifiers and source
- Literature Corpus work
- 20ab5c88-7419-5d04-8f61-c0ff4373cb35
- DOI
- 10.21203/rs.3.rs-8200314/v1
