Article

Activated Oncostatin M signaling drives cancer-associated skeletal muscle wasting

2023-01-27

Abstract excerpt

<h4>Summary</h4> Progressive weakness and muscle loss are associated with multiple chronic conditions including muscular dystrophy and cancer. Cancer-associated cachexia, characterized by dramatic weight loss and fatigue, leads to reduced quality of life and poor survival. Inflammatory cytokines have been implicated in muscle atrophy, however, available anti-cytokine therapies failed to prevent muscle wasting in...

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Literature Corpus work: 7e137a36-aa61-5fd4-b362-9cdd5455320d
DOI: 10.1101/2023.01.26.525658

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