Article

EDA2R/NIK signaling promotes skeletal muscle atrophy linked to cancer cachexia

2023-01-23

Abstract excerpt

<h4>Summary</h4> Skeletal muscle atrophy is a hallmark of the cachexia syndrome that is associated with poor survival and reduced quality of life in cancer patients 1 . Muscle atrophy involves excessive protein catabolism and loss of muscle mass and strength 2 . An effective therapy against muscle wasting is lacking as mechanisms driving the atrophy process remain incompletely understood. Our gene expression an...

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Literature Corpus work: 669d5c91-f099-5a25-8fc8-bfc9b67cd754
DOI: 10.1101/2023.01.23.525138

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