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Article

Oncostatin M: Dual Regulator of the Skeletal and Hematopoietic Systems

10 Jan 2024

Abstract excerpt

PURPOSE OF THE REVIEW: The bone and hematopoietic tissues coemerge during development and are functionally intertwined throughout mammalian life. Oncostatin M (OSM) is an inflammatory cytokine of the interleukin-6 family produced by osteoblasts, bone marrow macrophages, and neutrophils. OSM acts via two heterodimeric receptors comprising GP130 with either an OSM receptor (OSMR) or a leukemia inhibitory factor...

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PMID: 38198032
DOI: 10.1007/s11914-023-00837-z

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