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A conserved immunometabolic transcriptional programme defines MASLD progression and is maintained in hepatocellular carcinoma

2026-04-07

Abstract excerpt

<title>Abstract</title> <p>Metabolic dysfunction–associated steatotic liver disease (MASLD) constitutes a primary cause of hepatocellular carcinoma (HCC). However, the transcriptional programs linking disease progression to tumor biology remain incompletely defined. Here, we aimed to identify conserved transcriptional programs underlying MASLD progression and to determine their biological organization, cellular c...

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Literature Corpus work
7dfefcc1-08e5-56ff-b944-6e6a195d253f
DOI
10.21203/rs.3.rs-9310352/v1
Open publication

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A conserved immunometabolic transcriptional programme defines MASLD progression and is maintained in hepatocellular carcinomaDOI 10.21203/rs.3.rs-9310352/v1
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