Article
Pathophysiology of acute respiratory syndrome coronavirus 2 infection: a systematic literature review to inform EULAR points to consider.
RMD open - 1 Feb 2021
Najm Aurélie, Alunno Alessia, Mariette Xavier, Terrier Benjamin, De Marco Gabriele, Emmel Jenny, Mason Laura, McGonagle Dennis G, Machado Pedro M
Abstract excerpt
BACKGROUND: The SARS-CoV-2 pandemic is a global health problem. Beside the specific pathogenic effect of SARS-CoV-2, incompletely understood deleterious and aberrant host immune responses play critical roles in severe disease. Our objective was to summarise the available information on the pathophysiology of COVID-19. METHODS: Two reviewers independently identified eligible studies according to the following PICO...
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