Article

Type I, II, and III interferon signatures correspond to COVID-19 disease severity

2021-03-12

Abstract excerpt

We analyzed the plasma levels of interferons and cytokines, and the expression of interferon-stimulated genes in peripheral blood mononuclear cells in COVID-19 patients with different disease severity. Mild patients exhibited transient type I interferon responses, while ICU patients had prolonged type I interferon responses with hyper-inflammation mediated by interferon regulatory factor 1. Type II interferon resp...

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Identifiers and source

Literature Corpus work: bbe9158b-c028-558b-b8e3-14cad364f020
DOI: 10.1101/2021.03.10.21253317

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