Article

Spt6 is a maintenance factor for centromeric CENP-A

2019-02-25

Abstract excerpt

Replication and transcription of genomic DNA requires partial disassembly of nucleosomes to allow progression of polymerases. This constitutes both an opportunity to remodel the underlying chromatin as well as the potential danger of losing epigenetic information. Centromeric transcription has been shown to be required for stable incorporation of the centromere-specific histone dCENP-A in M/G1-phase, which depends...

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Literature Corpus work: 7da6e607-8245-5545-8569-524b7bbb674a
DOI: 10.1101/560300

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