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A microglia-containing cerebral organoid model to study early life immune challenges

2024-05-26

Abstract excerpt

Prenatal infections and activation of the maternal immune system have been proposed to contribute to causing neurodevelopmental disorders (NDDs), chronic conditions often linked to brain abnormalities. Microglia are the resident immune cells of the brain and play a key role in neurodevelopment. Disruption of microglial functions can lead to brain abnormalities and increase the risk of developing NDDs. How the mate...

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Literature Corpus work
7da53238-7770-5081-909c-6da257de24f5
DOI
10.1101/2024.05.24.595814
Open publication

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A microglia-containing cerebral organoid model to study early life immune challengesDOI 10.1101/2024.05.24.595814
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