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Article

How microbiota shape microglial phenotypes and epigenetics.

Glia - 1 Aug 2020

Erny Daniel, Prinz Marco

Abstract excerpt

Among the myeloid cells in the central nervous system (CNS) microglia are the main representatives of the innate immune system. Microglial fulfil tasks beyond phagocytosing debris and host defense against invading microorganism. During brain development microglia guide for example neurons for proper CNS formation, in adulthood they maintain tissue homeostasis and in aging microglia may become pro-inflammatory and...

Topics

Animals
Central Nervous System
Homeostasis
Humans
Microbiota
Microglia
Neurons
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32181523
DOI: 10.1002/glia.23822

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