Article
The Functions of ZIP8, ZIP14, and ZnT10 in the Regulation of Systemic Manganese Homeostasis.
International journal of molecular sciences - 7 May 2020
Winslow James W W, Limesand Kirsten H, Zhao Ningning
Abstract excerpt
As an essential nutrient, manganese is required for the regulation of numerous cellular processes, including cell growth, neuronal health, immune cell function, and antioxidant defense. However, excess manganese in the body is toxic and produces symptoms of neurological and behavioral defects, clinically known as manganism. Therefore, manganese balance needs to be tightly controlled. In the past eight years,...
Topics
- Animals
- Cation Transport Proteins
- Homeostasis
- Humans
- Intestinal Absorption
- Manganese
- Manganese Poisoning
- Mutation