Article

Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis

2024-03-30

Abstract excerpt

The enteric nervous system (ENS) senses microbiota-derived signals and orchestrates mucosal immunity and epithelial barrier functions, in health and disease. However, mechanistic dissections of intestinal neuro-immune-microbiota communications remain challenging and existing research methods limit experimental controllability and throughput. Here, we present a novel optogenetics-integrated gut organ culture system...

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Literature Corpus work: 7d8f6bfa-8f1a-59f3-9954-566811589fc1
DOI: 10.1101/2024.03.28.587149

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