Article

Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasia

2024-11-29

Abstract excerpt

Intestinal tuft cells are epithelial sentinels that trigger host defense upon detection of parasite-derived compounds. While representing interesting targets for immunomodulatory therapies in inflammation-driven intestinal diseases, their detailed functioning is poorly understood. Although two distinct intestinal tuft cell types have been described, we reveal common intermediary transcriptomes among tuft cells in...

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Identifiers and source

Literature Corpus work: 7344bb29-c356-511b-91b1-236ac5714e26
DOI: 10.1101/2024.11.28.625899

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