Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prototypical pacemaker neurons interact with the resident microbiota

9 Jul 2020

Abstract excerpt

Significance Here, we discover prototypical pacemaker neurons in the ancient cnidarian Hydra and provide evidence for a direct interaction of these neurons with the commensal microbiota. We uncover a remarkable gene-expression program conservation between the Hydra pacemaker neurons and pacemaker cells in Caenorhabditis elegans and the mammalian gut. We suggest that prototypical pacemaker cells emerged as neurons...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian rhythm and melatonin
Share to Dietary Effects on Health
Share to Genetics, Aging, and Longevity in Model Organisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32647059
DOI: 10.1073/pnas.1920469117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prototypical pacemaker neurons interact with the resident microbiotaPMID 32647059Read ↗

Prototypical pacemaker neurons are immunocompetent cellsSemantic proximity Read ↗

Emergence of Caenorhabditis elegans as a Model Organism for Dissecting the Gut–Brain AxisSemantic proximity Read ↗

The enteric nervous system of the human and mouse colon at a single-cell resolutionSemantic proximity Read ↗

Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasisSemantic proximity Read ↗

Healthy Intestinal Function Relies on Coordinated Enteric Nervous System, Immune System, and Epithelium ResponsesSemantic proximity Read ↗

A calcium wave mediated by gap junctions coordinates a rhythmic behavior in C. elegans.Semantic proximity Read ↗

Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic levelSemantic proximity Read ↗

Identification of bacterial signals that modulate enteric sensory neurons to influence behavior in C. elegansSemantic proximity Read ↗

You Talking to Me? Says the Enteric Nervous System (ENS) to the Microbe. How Intestinal Microbes Interact with the ENSSemantic proximity Read ↗

Gut-innervating nociceptor neurons protect against enteric infection by modulating the microbiota and Peyer’s patch microfold cellsSemantic proximity Read ↗

L-Cells are the Functional Neuropod Cell in Human Gastrointestinal Tract and are Dysregulated in Inflammatory Bowel Disease (IBD)Semantic proximity Read ↗

Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.