Article

ENS lineage potential is not intrinsically regionalized but is modulated by PTPRZ1 signaling

2026-03-07

Abstract excerpt

<h4>ABSTRACT</h4> The enteric nervous system (ENS) orchestrates critical gastrointestinal functions including peristalsis, fluid exchange, and blood flow regulation, and develops from vagal neural crest (vNC) progenitors that colonize the gut. While the gut epithelium and mesenchyme exhibit pronounced anterior–posterior (A-P) transcriptional patterning and lineage diversification after mid-gestation, whether the...

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Literature Corpus work: 400cc1f4-e869-5d9a-a193-bfc7d417a9ad
DOI: 10.64898/2026.03.05.709942

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