Article

A neuroimmune IL-13 axis is associated with human enteric nervous system development

2026-05-28

Abstract excerpt

The mechanisms governing maturation of the human enteric nervous system (ENS) during early postnatal life remain poorly defined. Here, we characterize the transcriptomic, cellular, and functional landscape of the neonatal human ileum and identify a neuro-immune axis associated with ENS expansion. Using human tissue transcriptomics, flow cytometry, iPSC-derived enteric neural lineages, and single-cell interactome a...

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Identifiers and source

Literature Corpus work: 3db6349e-353e-5094-a3bb-77d6af309d64
DOI: 10.64898/2026.05.27.728110

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