Article

Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations

2023-11-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Smooth muscle cells (SMCs), which make up the medial layer of arteries, are key cell types involved in cardiovascular diseases (CVD), the leading cause of mortality and morbidity worldwide. In response to microenvironment alterations, SMCs dedifferentiate from a “contractile” to a “synthetic” phenotype characterized by an increased proliferation, migration, production of extra...

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Literature Corpus work: 7d83731e-02b2-5ce2-920c-00435f071eed
DOI: 10.1101/2023.11.10.23298351

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