Article

BRAF deletion in adult patients with Langerhans cell histiocytosis correlates with multisystem disease and poor outcome

2024-05-21

Abstract excerpt

<title>Abstract</title> <p>Langerhans cell histiocytosis (LCH) is a rare and highly heterogeneous histiocytosis. The objective of this study was to characterize the genomic landscape of adult LCH and correlate molecular findings with clinical features and patient outcomes. This study included 254 patients aged ≥18 years with biopsy-proven LCH from January 2000 to December 2023. All patients underwent next-generat...

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Literature Corpus work: 7d482309-a3ce-5bc7-ae64-daa15834b8b4
DOI: 10.21203/rs.3.rs-4283207/v1

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