Article

Clinical characteristics, genomic profiling, treatments, and outcomes of Langerhans Cell Sarcoma

2025-09-26

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Langerhans cell sarcoma (LCS), an exceptionally rare and aggressive neoplasm, remains poorly characterized due to its scarcity. To address this knowledge gap, we conducted a retrospective analysis of 13 LCS patients. This retrospective study included patients ≥18 years old with biopsy proven LCS from October 2015 to April 2025. <bold>Results:</bold> The med...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4d9c0e07-f359-58dd-929a-6e8954a5ef63
DOI: 10.21203/rs.3.rs-7445461/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Clinical characteristics, genomic profiling, treatments, and outcomes of Langerhans Cell SarcomaDOI 10.21203/rs.3.rs-7445461/v1Read

Clinical characteristics, genomic profiling, treatments, and outcomes of Langerhans cell sarcoma.Semantic proximity Read

Clinical and prognostic features of Langerhans cell histiocytosis in adults.Semantic proximity Read

A Case of Pulmonary Langerhans Cell Sarcoma Simultaneously Diagnosed with Cutaneous Langerhans Cell Histiocytosis Studied by Whole-Exome Sequencing.Semantic proximity Read

Sorafenib Combined with DOAP Regimen for the Treatment of BRAF V600E-Negative Langerhans Cell Sarcoma: A three-year follow-up resultSemantic proximity Read

A case of Langerhans cell sarcoma on the scalp: Whole-exome sequencing reveals a role of ultraviolet in the pathogenesis.Semantic proximity Read

BRAF Mutated LCH: Diagnosis and Treatment Challenges - A High-Risk Case Presentation and Discussion.Semantic proximity Read

Identification of BRAF V600E‑negative and MAP2K1‑posivtive mutations in an adolescent with Langerhans cell histiocytosis: a case report combined with next-generation sequencing analysisSemantic proximity Read

BRAF deletion in adult patients with Langerhans cell histiocytosis correlates with multisystem disease and poor outcomeSemantic proximity Read

Recent advances in the understanding of Langerhans cell histiocytosisSemantic proximity Read

[Langerhans cell sarcoma: a clinicopathologic analysis of four cases].Semantic proximity Read

Advances in our understanding of genetic markers and targeted therapies for pediatric LCH.Semantic proximity Read

BRAF Deletion in Adult Patients with Langerhans Cell Histiocytosis Correlates with Multisystem Disease and Poor Outcomes.Semantic proximity Read