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Article

Clinical and prognostic features of Langerhans cell histiocytosis in adults.

Cancer science - 1 Sept 2023

Sato Aki, Kobayashi Masayuki, Yusa Nozomi, Ogawa Miho, Shimizu Eigo, Kawamata Toyotaka, Yokoyama Kazuaki, Ota Yasunori, Ichinohe Tatsuo, Ohno Hitoshi, Mori Yasuo, Sakaida Emiko, Kondo Tadakazu, Imoto Seiya, Nannya Yasuhito, Mitani Kinuko, Tojo Arinobu

Abstract excerpt

Langerhans cell histiocytosis (LCH) is a rare disease characterized by clonal expansion of CD1a+ CD207+ myeloid dendritic cells. The features of LCH are mainly described in children and remain poorly defined in adults; therefore, we conducted a nationwide survey to collect clinical data from 148 adult patients with LCH. The median age at diagnosis was 46.5 (range: 20-87) years with male predominance (60.8%)....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 37364599
DOI: 10.1111/cas.15879
PMCID: PMC10475785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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