Article

Whole-body modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease

2023-09-06

Abstract excerpt

<title>Abstract</title> <p>In this study, we aimed to understand the potential role of the gut microbiome in the development of Alzheimer's disease (AD). We took a multi-faceted approach to investigate this relationship. Urine metabolomics were examined in individuals with AD and controls, revealing decreased formate and fumarate concentrations in AD. Additionally, we utilized whole-genome sequencing (WGS) data o...

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Literature Corpus work: 7d214968-220f-5632-afde-f555cec85d93
DOI: 10.21203/rs.3.rs-3306891/v1

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