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Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer’s disease

2 Oct 2024

Abstract excerpt

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder with a global impact, yet its pathogenesis remains poorly understood. While age, metabolic abnormalities, and accumulation of neurotoxic substances are potential risk factors for AD, their effects are confounded by other factors. To address this challenge, we first utilized multi-omics data from 87 well phenotyped AD patients and generated...

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PMID: 39358810
DOI: 10.1186/s13195-024-01578-6

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