Article

Microbiome functional gene pathways predict cognitive performance in older adults with Alzheimer’s disease

2025-03-11

Abstract excerpt

<h4>ABSTRACT</h4> Disturbances in the gut microbiome is increasing correlated with neurodegenerative disorders, including Alzheimer’s Disease. The microbiome may in fact influence disease pathology in AD by triggering or potentiating systemic and neuroinflammation, thereby driving disease pathology along the “microbiota-gut-brain-axis”. Currently, drivers of cognitive decline and symptomatic progression in AD rem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0b01ac46-58ff-5762-ac6e-899e77085593
DOI: 10.1101/2025.03.06.641911

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Microbiome functional gene pathways predict cognitive performance in older adults with Alzheimer’s diseaseDOI 10.1101/2025.03.06.641911Read

Gut microbiome compositional and functional features associate with Alzheimer's disease pathologySemantic proximity Read

The link between gut microbiome and Alzheimer's disease: From the perspective of new revised criteria for diagnosis and staging of Alzheimer's diseaseSemantic proximity Read

Unique trans-kingdom microbiome structural and functional signatures predict cognitive decline in older adultsSemantic proximity Read

Gut microbiome composition may be an indicator of preclinical Alzheimer’s diseaseSemantic proximity Read

Gut Microbiome and Risk of Dementia –a Prospective, Population-Based StudySemantic proximity Read

Gut microbiome alterations in Alzheimer’s diseaseSemantic proximity Read

The Microbiota–Gut–Brain Axis in Alzheimer’s Disease: A Review of Taxonomic Alterations and Potential Avenues for InterventionsSemantic proximity Read

Metagenomic analysis characterizes stage-specific gut microbiota in Alzheimer’s diseaseSemantic proximity Read

Gut microbiome alterations in preclinical Alzheimer’s diseaseSemantic proximity Read

Towards understanding brain-gut-microbiome connections in Alzheimer’s diseaseSemantic proximity Read

Signature of Alzheimer’s Disease in Intestinal Microbiome: Results From the AlzBiom StudySemantic proximity Read

Gut microbiome‐derived metabolites in Alzheimer's disease: Regulation of immunity and potential for therapeuticsSemantic proximity Read