Article

Repurposing Cilnidipine as an Entry Inhibitor Against Crimean–Congo Haemorrhagic Fever Pseudovirus Infection

2025-12-23

Abstract excerpt

<title>Abstract</title> <p>Crimean-Congo haemorrhagic fever virus (CCHFV), a tick-borne pathogen of the Nairoviridae family, is classified as a high-risk biosafety level-4 (BSL-4) agent, which restricts its handling and limits mechanistic investigations. To overcome these challenges, we developed a CCHFV pseudovirus as a safe and reliable surrogate for studying viral entry and evaluating antiviral candidates. Pse...

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Identifiers and source

Literature Corpus work: 7d08309e-6058-5d5f-9866-e7a944e8a3ce
DOI: 10.21203/rs.3.rs-8320594/v1

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