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The calcium channel inhibitor lacidipine inhibits Zika virus replication in neural progenitor cells

31 Mar 2022

Abstract excerpt

After decades of being considered non-pathogenic, Zika virus (ZIKV) emerged as an important threat to human health during the epidemic of 2015–2016. ZIKV infections are usually asymptomatic, but can cause Guillain-Barré syndrome in adults and microcephaly in newborns. As there are currently no approved antiviral drugs against ZIKV, we tested anti-ZIKV activity of compounds from the NIH Clinical Collection for...

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PMID: 35367280
DOI: 10.1016/j.antiviral.2022.105313

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