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Drug repurposing approach against chikungunya virus: an in vitro and in silico study

27 Apr 2023

Abstract excerpt

The chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes mosquitoes. There are no licenced antivirals or vaccines for treatment or prevention. Drug repurposing approach has emerged as a novel concept to find alternative uses of therapeutics to battle pathogens. In the present study, anti CHIKV activity of fourteen FDA-approved drugs was investigated by in vitro and in silico approaches. Focus-forming...

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Identifiers

PMID: 37180434
DOI: 10.3389/fcimb.2023.1132538

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