Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-throughput drug screening using the Ebola virus transcription- and replication-competent virus-like particle system

24 Aug 2018

Abstract excerpt

The massive epidemic of Ebola virus disease (EVD) in West Africa, followed in recent months by two outbreaks in the Democratic Republic of the Congo, underline the importance of this severe disease. Because Ebola virus (EBOV) must be manipulated under biosafety level 4 (BSL4) containment, the discovery and development of virus-specific therapies have been hampered. Recently, a transient transfection-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral gastroenteritis research and epidemiology
Share to Viral Infections and Outbreaks Research
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30149038
DOI: 10.1016/j.antiviral.2018.08.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-throughput drug screening using the Ebola virus transcription- and replication-competent virus-like particle systemPMID 30149038Read ↗

Ebolavirus Entry: From Molecular Characterization to Drug DiscoverySemantic proximity Read ↗

High-Throughput Assays Using a Luciferase-Expressing Replicon, Virus-Like Particles, and Full-Length Virus for West Nile Virus Drug DiscoverySemantic proximity Read ↗

A panel of biologically contained orthoebolaviruses for the screening of broad-spectrum antiviralsSemantic proximity Read ↗

Evaluation of Fendiline Treatment in VP40 System with Nucleation-Elongation Process: A Computational Model of Ebola Virus Matrix Protein AssemblySemantic proximity Read ↗

High-throughput, luciferase-based reverse genetics systems for identifying inhibitors of Marburg and Ebola virusesSemantic proximity Read ↗

A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycleSemantic proximity Read ↗

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic MinigenomesSemantic proximity Read ↗

A cell-based screening system for influenza A viral RNA transcription/replication inhibitorsSemantic proximity Read ↗

Ebolavirus: A Brief Review of Novel Therapeutic TargetsSemantic proximity Read ↗

Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2Semantic proximity Read ↗

A Novel Life Cycle Modeling System for Ebola Virus Shows a Genome Length-Dependent Role of VP24 in Virus InfectivitySemantic proximity Read ↗

Novel Stable Ebola Virus Minigenome Replicon Reveals Remarkable Stability of the Viral GenomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.