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Loss of age-accumulated <i>crh-1</i> circRNAs ameliorate amyloid β-induced toxicity in a <i>C. elegans</i> model for Alzheimer’s disease

2024-04-13

Abstract excerpt

<h4>ABSTRACT</h4> Circular RNAs (circRNAs) are non-coding RNAs mostly derived from exons of protein-coding genes via a back-splicing process. The expression of hundreds of circRNAs accumulates during healthy aging and is associated with Alzheimer’s disease (AD), characterized by the accumulation of amyloid-beta (Aβ) proteins. In C. elegans , many circRNAs were previously found to accumulate during aging, with lo...

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Literature Corpus work
7d019d1b-3927-5d3c-92a5-3a06de33caf2
DOI
10.1101/2024.04.09.588761
Open publication

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Loss of age-accumulated <i>crh-1</i> circRNAs ameliorate amyloid β-induced toxicity in a <i>C. elegans</i> model for Alzheimer’s diseaseDOI 10.1101/2024.04.09.588761
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