Article

Polygenic risk score from a multi-ancestry GWAS uncovers susceptibility of heart failure

2021-12-07

Abstract excerpt

<h4>SUMMARY</h4> Identifying individuals at high risk of heart failure during precursor stages could allow for earlier initiation of treatments to modify disease progression. We performed a GWAS meta- analysis to generate a heart failure (HF) polygenic risk score (PRS) then tested the association with phenotypic subtypes (reduced ejection fraction [HFrEF] and preserved ejection fraction [HFpEF]) to evaluate the va...

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Literature Corpus work: 7cff95ba-ef9c-50e9-8a9c-8b12b3cfa8be
DOI: 10.1101/2021.12.06.21267389

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