Article
A Novel <i>Tmem119-tdTomato</i> Reporter Mouse Model for Studying Microglia in the Central Nervous System
2019-06-10
Abstract excerpt
Microglia are resident immune cells of the central nervous system (CNS). The exact role of microglia in the physiopathology of CNS disorders is not clear due to lack of tools to discriminate between CNS resident and infiltrated innate immune cells. Here, we present a novel reporter mouse model targeting a microglia-specific marker (TMEM119) for studying the function of microglia in health and disease. By placing a...
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Identifiers and source
- Literature Corpus work
- 7cf9d63e-db98-52f1-9ce7-98cc002eabd3
- DOI
- 10.1101/665893