Article

Highly efficient and versatile plasmid-based gene editing in primary T cells

2018-01-13

Abstract excerpt

Adoptive cell transfer (ACT) is an important approach for basic research and emerges as an effective treatment for various diseases including infections and blood cancers. Direct genetic manipulation of primary immune cells opens up unprecedented research opportunities and could be applied to enhance cellular therapeutic products. Here, we report highly efficient genome engineering in primary murine T cells using...

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Literature Corpus work: 7cf3d606-dad6-5e10-8af7-2ae5d45dfc8d
DOI: 10.1101/247544

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