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Article

Highly Efficient and Versatile Plasmid-Based Gene Editing in Primary T Cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2018

Kornete Mara, Marone Romina, Jeker Lukas T

Abstract excerpt

Adoptive cell transfer is an important approach for basic research and emerges as an effective treatment for various diseases, including infections and blood cancers. Direct genetic manipulation of primary immune cells opens up unprecedented research opportunities and could be applied to enhance cellular therapeutic products. In this article, we report highly efficient genome engineering in primary murine T cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29445007
DOI: 10.4049/jimmunol.1701121
PMCID: PMC5857648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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