Heterogeneous effects of antidepressants on suicidal ideation: role of polygenic scores

Abstract excerpt

Depression continues to be a major contributor to the global burden of diseases. Antide-pressants are recommended as the initial choice of treatment for moderate and severe depression among adults, but the choice of antidepressant class can be challenging, as efficacies of commonly used antidepressants are generally comparable between classes. As such, to determine which medication to prescribe to each patient, cl...

Topics

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• Antidepressive Agents
• Black or African American
• Hispanic or Latino
• Major Depressive Disorder
• Multifactorial Inheritance
• Selective Serotonin Reuptake Inhibitors
• Treatment Outcome
• White

Identifiers and source

Literature Corpus work

7cf330b3-8c19-5300-82e1-b75b3929d3d2

DOI

10.1101/2024.11.02.24316657