Article

Pharmacogenetics of antidepressant response: a polygenic approach

2016-12-14

Abstract excerpt

<h4>Background</h4> Major depressive disorder (MDD) has a high personal and socio-economic burden and more than 60% of patients fail to achieve remission with the first antidepressant. The biological mechanisms behind antidepressant response are only partially known but genetic factors play a relevant role. A combined predictor across genetic variants may be useful to investigate this complex trait. <h4>Methods</...

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Literature Corpus work: 4231ff25-b3b9-5d8b-8635-c972276048d4
DOI: 10.1101/093799

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