Article

Comprehensive Atomic-Scale 3D Viral-Host Protein Interactomes Enable Dissection of Key Mechanisms and Evolutionary Processes Underlying Viral Pathogenesis

2025-04-02

Abstract excerpt

Viral-human protein interactions are critical for viral replication and modulation of the host immune response. Structural modeling of these interactions is vital for developing effective antiviral therapies and vaccines. However, 99% of experimentally determined binary host-viral interactions currently lack structural information. We aimed to address this gap by leveraging computational protein structure predicti...

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Literature Corpus work: 7cb2c715-6584-5cb9-beb3-348d8b64c36d
DOI: 10.1101/2025.03.28.645946

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Comprehensive Atomic-Scale 3D Viral-Host Protein Interactomes Enable Dissection of Key Mechanisms and Evolutionary Processes Underlying Viral PathogenesisDOI 10.1101/2025.03.28.645946Read

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