Article

Systematic Validation of AlphaFold-Predicted Interactomes with LUCIA

2026-04-04

Abstract excerpt

Mapping protein-protein interactions (PPIs) at structural resolution is essential for understanding cellular machinery. While tools like AlphaFold enable proteome-wide structural predictions, the field lacks high-throughput experimental methods to verify these predictions at scale and establish empirical thresholds for confidence metrics, such as the widely used interface predicted Template Modeling (ipTM) score....

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Literature Corpus work: d8a8c5e0-4eb4-5b0c-95c0-85cc5cb4755a
DOI: 10.64898/2026.04.02.716051

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